On 5 May 2025, Biocon Biologics announced that it has entered multiple market access agreements in the US for Yesintek®, biosimilar to J&J’s Stelara® (ustekinumab). This includes the addition of Yeskintek® to the National Preferred Formulary (NPF) from 21 March 2025, Cigna’s commercial formulary from 21 March 2025, various United Healthcare formularies from 21 March 2025 and managed Medicaid from 1 March 2025. Yesintek® is also due to be added to Medicare from 1 June 2025, CVS Health from 1 July 2025 and Optum Rx from 1 July 2025.
Biocon launched Yesintek™ in the US in February 2025 following its approval in early December 2024 for multiple indications, including plaque psoriasis, active psoriatic arthritis, Crohn’s disease and ulcerative colitis.
In March 2025 Celltrion announced the addition of its ustekinumab biosimilar, Steqeyma® to the US Costco Member Prescription Program. According to Samsung Bioepis’ Q1/2025 US Biosimilar Market Report, ustekinumab biosimilar entrants to the US market in 2025 have provided steep WAC discounts of over 80%.